Macrophage stimulation in vitro by an inactive muramyl dipeptide derivative after conjugation to a multi-poly(DL-alanyl)-poly(L-lysine) carrier.

It has been previously reported that N-acetyl-muramyl-L-alanyl-D-isoglutamine (MDP), which represents the minimal structure that can substitute for mycobacteria in Freund complete adjuvant, activated macrophages in vitro and in vivo. In the present study we show that, in contrast to MDP, the nonadju...

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Опубликовано в: :Infect Immun
Главные авторы: Galelli, A, Le Garrec, Y, Chedid, L, Lefrancier, P, Derrien, M, Level, M
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1980
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC550884/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6769814/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.28.1.1-5.1980
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