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Association of schizophrenia onset age and white matter integrity with treatment effect of D-cycloserine: a randomized placebo-controlled double-blind crossover study

BACKGROUND: It has been reported that drugs which promote the N-Methyl-D-aspartate-type glutamate receptor function by stimulating the glycine modulatory site in the receptor improve negative symptoms and cognitive dysfunction in schizophrenia patients being treated with antipsychotic drugs. METHODS...

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Veröffentlicht in:BMC Psychiatry
Hauptverfasser: Takiguchi, Kazuo, Uezato, Akihito, Itasaka, Michio, Atsuta, Hidenori, Narushima, Kenji, Yamamoto, Naoki, Kurumaji, Akeo, Tomita, Makoto, Oshima, Kazunari, Shoda, Kosaku, Tamaru, Mai, Nakataki, Masahito, Okazaki, Mitsutoshi, Ishiwata, Sayuri, Ishiwata, Yasuyoshi, Yasuhara, Masato, Arima, Kunimasa, Ohmori, Tetsuro, Nishikawa, Toru
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508614/
https://ncbi.nlm.nih.gov/pubmed/28701225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12888-017-1410-3
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