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Complement factor 5 (C5) p.A252T mutation is prevalent in, but not restricted to, sub‐Saharan Africa: implications for the susceptibility to meningococcal disease
Complement C5 deficiency (C5D) is a rare primary immunodeficiency associated with recurrent infections, particularly meningitis, by Neisseria species. To date, studies to elucidate the molecular basis of hereditary C5D have included fewer than 40 families, and most C5 mutations (13 of 17) have been...
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| Publicado no: | Clin Exp Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5508369/ https://ncbi.nlm.nih.gov/pubmed/28369827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12967 |
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