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Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer
Tumor heterogeneity is considered a major cause for therapy resistance in colorectal cancer. Sub-populations of cells with different genetic alterations may exist in spatially distinct areas. Upon therapy, resistant sub-clones may enrich and ultimately lead to disease progression. Although ample dat...
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| Pubblicato in: | Histochem Cell Biol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Berlin Heidelberg
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5508037/ https://ncbi.nlm.nih.gov/pubmed/28321501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00418-017-1557-5 |
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