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Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer

Tumor heterogeneity is considered a major cause for therapy resistance in colorectal cancer. Sub-populations of cells with different genetic alterations may exist in spatially distinct areas. Upon therapy, resistant sub-clones may enrich and ultimately lead to disease progression. Although ample dat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Histochem Cell Biol
Prif Awduron: El-Heliebi, Amin, Kashofer, Karl, Fuchs, Julia, Jahn, Stephan W., Viertler, Christian, Matak, Andrija, Sedlmayr, Peter, Hoefler, Gerald
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508037/
https://ncbi.nlm.nih.gov/pubmed/28321501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00418-017-1557-5
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