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Osthole improves function of periodontitis periodontal ligament stem cells via epigenetic modification in cell sheets engineering

Inflammatory microenvironment causes the change of epigenetic modification in periodontal ligament stem cells derived from periodontitis tissues (P-PDLSCs), which results in defective osteogenic differentiation compared to cells from healthy tissues. It’s urgent to explore therapeutic strategies aim...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sun, Jin, Dong, Zhiwei, Zhang, Yang, He, Xiaoning, Fei, Dongdong, Jin, Fang, Yuan, Lin, Li, Bei, Jin, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507976/
https://ncbi.nlm.nih.gov/pubmed/28701802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05762-7
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