Free immunoglobulin light chain (FLC) promotes murine colitis and colitis-associated colon carcinogenesis by activating the inflammasome

Numerous studies have demonstrated that free Ig light chain (FLC), a novel inflammation mediator, participates in many inflammatory diseases by activating mast cells and extending the survival of neutrophils. However, it remains unclear whether FLC is involved in colitis and colitis-associated colon...

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Udgivet i:Sci Rep
Main Authors: Ma, Junfan, Jiang, Dongyang, Gong, Xiaoting, Shao, Wenwei, Zhu, Zhu, Xu, Weiyan, Qiu, Xiaoyan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507933/
https://ncbi.nlm.nih.gov/pubmed/28701727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05468-w
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