Beyond the Debye length in high ionic strength solution: direct protein detection with field-effect transistors (FETs) in human serum

In this study, a new type of field-effect transistor (FET)-based biosensor is demonstrated to be able to overcome the problem of severe charge-screening effect caused by high ionic strength in solution and detect proteins in physiological environment. Antibody or aptamer-immobilized AlGaN/GaN high e...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Chu, Chia-Ho, Sarangadharan, Indu, Regmi, Abiral, Chen, Yen-Wen, Hsu, Chen-Pin, Chang, Wen-Hsin, Lee, Geng-Yen, Chyi, Jen-Inn, Chen, Chih-Chen, Shiesh, Shu-Chu, Lee, Gwo-Bin, Wang, Yu-Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507911/
https://ncbi.nlm.nih.gov/pubmed/28701708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05426-6
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