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ESCRTs function directly on the lysosome membrane to downregulate ubiquitinated lysosomal membrane proteins

The lysosome plays an important role in maintaining cellular nutrient homeostasis. Regulation of nutrient storage can occur by the ubiquitination of certain transporters that are then sorted into the lysosome lumen for degradation. To better understand the underlying mechanism of this process, we pe...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Zhu, Lu, Jorgensen, Jeff R, Li, Ming, Chuang, Ya-Shan, Emr, Scott D
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507667/
https://ncbi.nlm.nih.gov/pubmed/28661397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26403
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