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Ganglioside and monosaccharide inhibition of nonspecific lymphocyte mitogenicity by group A streptococcal pyrogenic exotoxins.

Group A streptococcal pyrogenic exotoxins (SPE) types A, B, and C are potent nonspecific lymphocyte mitogens. The mitogenicity of these exotoxins was inhibited by gangliosides and sialic acid, whereas concanavalin A was unaffected. The capacity of both concanavalin A and SPE-A to stimulate lymphocyt...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Schlievert, P M, Schoettle, D J, Watson, D W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC550757/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6987174/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.27.1.276-279.1980
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