Gallic acid/hydroxypropyl-β-cyclodextrin complex: Improving solubility for application on in vitro/ in vivo Candida albicans biofilms

The aim of this study was to increase the solubility of gallic acid (GA) for the treatment of Candida albicans biofilm, which is very difficult to treat and requires high drug concentrations. Cyclodextrins (CDs) were used for this purpose. Complexes were evaluated by phase-solubility studies, prepar...

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Vydáno v:PLoS One
Hlavní autoři: Teodoro, Guilherme Rodrigues, Gontijo, Aline Vidal Lacerda, Borges, Aline Chiodi, Tanaka, Márcia Hiromi, Lima, Gabriela de Morais Gouvêa, Salvador, Marcos José, Koga-Ito, Cristiane Yumi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507443/
https://ncbi.nlm.nih.gov/pubmed/28700692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181199
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