Pediatric autoimmune hepatitis shows a disproportionate decline of regulatory T cells in the liver and of IL-2 in the blood of patients undergoing therapy

BACKGROUND & AIMS: The autoimmune hepatitis (AIH) is a chronic hepatitis driven by the adaptive immunity that affects all age groups. A functional and numerical regulatory T cell (Treg) defect has been reported in pediatric AIH (pAIH), while an intrahepatic increase in adult AIH (aAIH) patients...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Diestelhorst, Jana, Junge, Norman, Schlue, Jerome, Falk, Christine S., Manns, Michael P., Baumann, Ulrich, Jaeckel, Elmar, Taubert, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507441/
https://ncbi.nlm.nih.gov/pubmed/28700730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181107
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