Sulforaphane enhances irradiation effects in terms of perturbed cell cycle progression and increased DNA damage in pancreatic cancer cells

BACKGROUND: Sulforaphane (SFN), an herbal isothiocyanate enriched in cruciferous vegetables like broccoli and cauliflower, has gained popularity for its antitumor effects in cell lines such as pancreatic cancer. Antiproliferative as well as radiosensitizing properties were reported for head and neck...

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Bibliographic Details
Published in:PLoS One
Main Authors: Naumann, Patrick, Liermann, Jakob, Fortunato, Franco, Schmid, Thomas E., Weber, Klaus-Josef, Debus, Jürgen, Combs, Stephanie E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507286/
https://ncbi.nlm.nih.gov/pubmed/28700650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180940
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