New anthrarobin acyl derivatives as butyrylcholinesterase inhibitors: synthesis, in vitro and in silico studies

To treat Alzheimer's disease (AD), the available candidates are effective only against mild AD or have side effects. So, a study was planned to synthesis new candidates that may have good potential to treat AD. A series of new anthrarobin acyl derivatives (2–8) were synthesized by the reaction...

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Veröffentlicht in:Heliyon
Hauptverfasser: Lateef, Mehreen, Azhar, Abid, Siddiqui, Bina S., Zarina, Shamshad, uddin, Nizam, Anwar, Muhammad F., Siddiqui, Kauser, Azhar, Kaniz F., Iqbal, Lubna, Mehmood, Rashad, Perveen, Shagufta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506883/
https://ncbi.nlm.nih.gov/pubmed/28725871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2017.e00350
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