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Defective prostaglandin synthesis by C3H/HeJ mouse macrophages stimulated with endotoxin preparations.

Macrophages obtained from C3H/HeN mice produced significant amounts of prostaglandin E when exposed to phenol-extracted lipopolysaccharides (LPS), whereas macrophages from C3H/HeJ mice were unresponsive. The lipid A fraction from phenol-extracted LPS was an effective inducer or prostaglandin synthes...

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Autors principals: Wahl, L M, Rosenstreich, D L, Glode, L M, Sandberg, A L, Mergenhagen, S E
Format: Artigo
Idioma:Inglês
Publicat: 1979
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC550680/
https://ncbi.nlm.nih.gov/pubmed/422236
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