Diabetic rats present higher urinary loss of proteins and lower renal expression of megalin, cubilin, ClC‐5, and CFTR

Diabetic nephropathy (DN) occurs in around 40% of those with diabetes. Proteinuria is the main characteristic of DN and develops as a result of increased permeability of the glomerulus capillary wall and/or decreased proximal tubule endocytosis. The goal of this work was to evaluate renal function a...

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Publicado en:Physiol Rep
Main Authors: Figueira, Miriam F., Castiglione, Raquel C., de Lemos Barbosa, Carolina M., Ornellas, Felipe M., da Silva Feltran, Geórgia, Morales, Marcelo M., da Fonseca, Rodrigo N., de Souza‐Menezes, Jackson
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506523/
https://ncbi.nlm.nih.gov/pubmed/28676554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13335
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