Identification of tissue‐specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics

Caloric restriction (CR) without malnutrition has been shown to retard several aspects of the aging process and to extend lifespan in different species. There is strong interest in the identification of CR mimetics (CRMs), compounds that mimic the beneficial effects of CR on lifespan and healthspan...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Barger, Jamie L., Vann, James M., Cray, Nicole L., Pugh, Thomas D., Mastaloudis, Angela, Hester, Shelly N., Wood, Steven M., Newton, Michael A., Weindruch, Richard, Prolla, Tomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506434/
https://ncbi.nlm.nih.gov/pubmed/28556428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12608
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