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Biochemical isolation of myonuclei employed to define changes to the myonuclear proteome that occur with aging

Skeletal muscle aging is accompanied by loss of muscle mass and strength. Examining changes in myonuclear proteins with age would provide insight into molecular processes which regulate these profound changes in muscle physiology. However, muscle tissue is highly adapted for contraction and thus com...

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Detalles Bibliográficos
Publicado en:Aging Cell
Main Authors: Cutler, Alicia A., Dammer, Eric B., Doung, Duc M., Seyfried, Nicholas T., Corbett, Anita H., Pavlath, Grace K.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506426/
https://ncbi.nlm.nih.gov/pubmed/28544616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12604
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