Targeting Bacillosamine Biosynthesis in Bacterial Pathogens: Development of Inhibitors to a Bacterial Amino-Sugar Acetyltransferase from Campylobacter jejuni()

The glycoproteins of selected microbial pathogens often include highly modified carbohydrates such as 2,4-diacetamidobacillosamine (diNAcBac). These glycoconjugates are involved in host cell interactions and may be associated with the virulence of medically-significant Gram-negative bacteria. In lig...

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Bibliographic Details
Published in:J Med Chem
Main Authors: De Schutter, Joris W., Morrison, James P., Morrison, Michael J., Ciulli, Alessio, Imperiali, Barbara
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506375/
https://ncbi.nlm.nih.gov/pubmed/28182413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b01869
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