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Epigenetics and Cancer Stem Cells: Unleashing, Hijacking, and Restricting Cellular Plasticity

Epigenetic mechanisms have emerged as key players in cancer development which affect cellular states at multiple stages of the disease. During carcinogenesis, alterations in chromatin and DNA methylation resulting from genetic lesions unleash cellular plasticity and favor oncogenic cellular reprogra...

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Detalhes bibliográficos
Publicado no:Trends Cancer
Main Authors: Wainwright, Elanor N., Scaffidi, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506260/
https://ncbi.nlm.nih.gov/pubmed/28718414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2017.04.004
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