A novel protein kinase inhibitor IMB-YH-8 with anti-tuberculosis activity

Protein kinase B (PknB) is one of the Mycobacterium tuberculosis serine/threonine protein kinases and has an essential role in sustaining mycobacterial growth. Here, we identified and characterized a novel small molecule compound named IMB-YH-8 that inhibited PknB and served as anti-mycobacteria lea...

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Publicado no:Sci Rep
Main Authors: Xu, Jian, Wang, Ju-xian, Zhou, Jin-ming, Xu, Chang-liang, Huang, Bin, Xing, Yun, Wang, Bin, Luo, Rui, Wang, Yu-cheng, You, Xue-fu, Lu, Yu, Yu, Li-yan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506005/
https://ncbi.nlm.nih.gov/pubmed/28698545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04108-7
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