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Primary Cilia in Tumor Biology: The Primary Cilium as a Therapeutic Target in Cholangiocarcinoma

Cilia are microtubule-based organelles, which are ubiquitously expressed in epithelial cells. Cholangiocytes, the epithelial cells lining the biliary tree, have primary cilia extending from their apical plasma membrane into the ductal lumen, where the cilia function as multisensory organelles transd...

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Vydáno v:Curr Drug Targets
Hlavní autoři: Gradilone, Sergio A., Lorenzo Pisarello, María J., LaRusso, Nicholas F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505802/
https://ncbi.nlm.nih.gov/pubmed/25706257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1389450116666150223162737
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