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Pause & Go: from the discovery of RNA polymerase pausing to its functional implications

The synthesis of nascent RNA is a discontinuous process in which phases of productive elongation by RNA polymerase are interrupted by frequent pauses. Transcriptional pausing was first observed decades ago, but was long considered to be a special feature of transcription at certain genes. This view...

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Bibliographic Details
Published in:Curr Opin Cell Biol
Main Authors: Mayer, Andreas, Landry, Heather M., Churchman, L. Stirling
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505790/
https://ncbi.nlm.nih.gov/pubmed/28363125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2017.03.002
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