Novel assay reveals a large inducible replication competent HIV-1 reservoir in resting CD4(+) T cells

Although antiretroviral therapy can suppress HIV-1 infection to undetectable levels of plasma viremia, integrated latent HIV-1 genomes that encode replication competent virus persist in resting CD4(+) T cells. This latent HIV-1 reservoir represents a major barrier to a cure. Currently, there are sub...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Gupta, Phalguni, Sanyal, Anwesha, Ratner, Deena, Ding, Ming, Zerbato, Jennifer M., Giacobbi, Nicholas, Venkatachari, Narasimhan J., Patterson, Bruce K., Chargin, Amanda, Chen, Yue, Mailliard, Robbie B., Rinaldo, Charles R., Sluis-Cremer, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505781/
https://ncbi.nlm.nih.gov/pubmed/28553933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4347
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados