Antinociceptive tolerance to NSAIDs in the agranular insular cortex is mediated by opioid mechanism

Several lines of investigations have shown that in some brain areas, in particular, in the midbrain periaqueductal gray matter, rostral ventromedial medulla, central nucleus of amygdala, nucleus raphe magnus, and dorsal hippocampus, microinjections of nonsteroidal anti-inflammatory drugs (NSAIDs) in...

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Bibliographic Details
Published in:J Pain Res
Main Authors: Pirkulashvili, Natia, Tsiklauri, Nana, Nebieridze, Marina, Tsagareli, Merab G
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505549/
https://ncbi.nlm.nih.gov/pubmed/28740423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S138360
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