Golgi-associated PKC-ε is delivered to phagocytic cups: Role of PI4P()

PKC-ε concentration at phagocytic cups mediates the membrane fusion necessary for efficient IgG-mediated phagocytosis. The C1B and pseudosubstrate (εPS) domains are necessary and sufficient for this concentration. C1B binds diacylglycerol; the docking partner for εPS is unknown. Liposome assays reve...

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Udgivet i:J Immunol
Main Authors: Hanes, Cheryl M., D'Amico, Anna E., Ueyama, Takehiko, Wong, Alexander C., Zhang, Xuexin, Hynes, W. Frederick, Barroso, Margarida M., Cady, Nathaniel C., Trebak, Mohamed, Saito, Naoaki, Lennartz, Michelle R.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505341/
https://ncbi.nlm.nih.gov/pubmed/28539432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700243
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