Vandetanib-eluting Radiopaque Beads: In vivo Pharmacokinetics, Safety and Toxicity Evaluation following Swine Liver Embolization

PURPOSE: To evaluate the plasma and tissue pharmacokinetics, safety and toxicity following intra-arterial hepatic artery administration of Vandetanib (VTB)-eluting Radiopaque Beads (VERB) in healthy swine. MATERIALS AND METHODS: In a first phase, healthy swine were treated with hepatic intra-arteria...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Denys, Alban, Czuczman, Peter, Grey, David, Bascal, Zainab, Whomsley, Rhys, Kilpatrick, Hugh, Lewis, Andrew L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505051/
https://ncbi.nlm.nih.gov/pubmed/28740542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.19652
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