Normal versus Pathological Cardiac Fibroblast-Derived Extracellular Matrix Differentially Modulates Cardiosphere-Derived Cell Paracrine Properties and Commitment

Human resident cardiac progenitor cells (CPCs) isolated as cardiosphere-derived cells (CDCs) are under clinical evaluation as a therapeutic product for cardiac regenerative medicine. Unfortunately, limited engraftment and differentiation potential of transplanted cells significantly hamper therapeut...

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Veröffentlicht in:Stem Cells Int
Hauptverfasser: Pagano, Francesca, Angelini, Francesco, Castaldo, Clotilde, Picchio, Vittorio, Messina, Elisa, Sciarretta, Sebastiano, Maiello, Ciro, Biondi-Zoccai, Giuseppe, Frati, Giacomo, Meglio, Franca di, Nurzynska, Daria, Chimenti, Isotta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504962/
https://ncbi.nlm.nih.gov/pubmed/28740514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7396462
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