PAT-H-MS coupled with laser microdissection to study histone post-translational modifications in selected cell populations from pathology samples

BACKGROUND: Aberrations in histone post-translational modifications (hPTMs) have been linked with various pathologies, including cancer, and could not only represent useful biomarkers but also suggest possible targetable epigenetic mechanisms. We have recently developed an approach, termed pathology...

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Bibliographic Details
Published in:Clin Epigenetics
Main Authors: Noberini, Roberta, Longuespée, Rémi, Richichi, Cristina, Pruneri, Giancarlo, Kriegsmann, Mark, Pelicci, Giuliana, Bonaldi, Tiziana
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Methodology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504751/
https://ncbi.nlm.nih.gov/pubmed/28702092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0369-8
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