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An agent-based model of triple-negative breast cancer: the interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia

BACKGROUND: Triple-negative breast cancer lacks estrogen, progesterone, and HER2 receptors and is thus not possible to treat with targeted therapies for these receptors. Therefore, a greater understanding of triple-negative breast cancer is necessary for the treatment of this cancer type. In previou...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Norton, Kerri-Ann, Wallace, Travis, Pandey, Niranjan B., Popel, Aleksander S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504656/
https://ncbi.nlm.nih.gov/pubmed/28693495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0445-x
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