Exploring the relationship between α-actinin-3 deficiency and obesity in mice and humans

Obesity is a worldwide health crisis, and the identification of genetic modifiers of weight gain is crucial in understanding this complex disorder. A common null polymorphism in the fast fiber-specific gene ACTN3 (R577X) is known to influence skeletal muscle function and metabolism. α-Actinin-3 defi...

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Foilsithe in:Int J Obes (Lond)
Main Authors: Houweling, P J, Berman, Y D, Turner, N, Quinlan, K G R, Seto, J T, Yang, N, Lek, M, Macarthur, D G, Cooney, G, North, K N
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2017
Ábhair:
Short Communication
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504447/
https://ncbi.nlm.nih.gov/pubmed/28293018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2017.72
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