High salt induces autocrine actions of ET-1 on inner medullary collecting duct NO production via upregulated ET(B) receptor expression

The collecting duct endothelin-1 (ET-1), endothelin B (ET(B)) receptor, and nitric oxide synthase-1 (NOS1) pathways are critical for regulation of fluid-electrolyte balance and blood pressure control during high-salt feeding. ET-1, ET(B) receptor, and NOS1 are highly expressed in the inner medullary...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Hyndman, Kelly Anne, Dugas, Courtney, Arguello, Alexandra M., Goodchild, Traci T., Buckley, Kathleen M., Burch, Mariah, Yanagisawa, Masashi, Pollock, Jennifer S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Fluid and Electrolyte Homeostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504420/
https://ncbi.nlm.nih.gov/pubmed/27280426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00016.2015
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