Autophagy is involved in adipogenic differentiation by repressesing proteasome-dependent PPARγ2 degradation

Animal studies have shown that autophagy is essential in the process of obesity. Here, we performed daily injection of the autophagy inhibitor chloroquine (CQ) in mice and found that systemic administration of CQ blocks high-fat diet-induced obesity. To investigate the potential underlying molecular...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Zhang, Chongben, He, Yingke, Okutsu, Mitsuhara, Ong, Lai Chun, Jin, Yi, Zheng, Lin, Chow, Pierce, Yu, Sidney, Zhang, Mei, Yan, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504416/
https://ncbi.nlm.nih.gov/pubmed/23800883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00640.2012
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