Localization and role of metabotropic glutamate receptors subtype 5 in the gastrointestinal tract

Metabotropic glutamate receptor subtype 5 (mGluR5) is a Group I mGlu subfamily of receptors coupled to the inositol trisphosphate/diacylglycerol pathway. Like other mGluR subtypes, mGluR5s contain a phylogenetically conserved, extracellular orthosteric binding site and a more variable allosteric bin...

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Bibliographic Details
Published in:World J Gastroenterol
Main Authors: Ferrigno, Andrea, Berardo, Clarissa, Di Pasqua, Laura G, Siciliano, Veronica, Richelmi, Plinio, Vairetti, Mariapia
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504365/
https://ncbi.nlm.nih.gov/pubmed/28740338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v23.i25.4500
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