Rosmarinic Acid Protects against Inflammation and Cardiomyocyte Apoptosis during Myocardial Ischemia/Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma

The cardiac ischemia-reperfusion (I/R) injury greatly influences the therapeutic effect and remains an urgent challenge in clinical therapy. Polypharmacology opens a new therapeutic opportunity to design drugs with a specific target for improving the efficacy. In this study, we first forecasted that...

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Pubblicato in:Front Pharmacol
Autori principali: Han, Jichun, Wang, Dong, Ye, Lei, Li, Peng, Hao, Wenjin, Chen, Xiaoyu, Ma, Jun, Wang, Bo, Shang, Jing, Li, Defang, Zheng, Qiusheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504166/
https://ncbi.nlm.nih.gov/pubmed/28744220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00456
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