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Amylin acts in the lateral dorsal tegmental nucleus to regulate energy balance through GABA signaling

BACKGROUND: The pancreatic- and brain-derived hormone amylin promotes negative energy balance and is receiving increasing attention as a promising obesity therapeutic. However, the neurobiological substrates mediating amylin’s effects are not fully characterized. We postulated that amylin acts in th...

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Detalles Bibliográficos
Publicado en:Biol Psychiatry
Autores principales: Reiner, David J., Mietlicki-Baase, Elizabeth G., Olivos, Diana R., McGrath, Lauren E., Zimmer, Derek J., Koch-Laskowski, Kieran, Krawczyk, Joanna, Turner, Christopher, Noble, Emily E., Hahn, Joel D., Schmidt, Heath D., Kanoski, Scott E., Hayes, Matthew R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503810/
https://ncbi.nlm.nih.gov/pubmed/28237459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.12.028
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