Reduced mouse allergen is associated with epigenetic changes in regulatory genes, but not mouse sensitization, in asthmatic children

Chronic exposure to mouse allergen may contribute greatly to the inner-city asthma burden. We hypothesized that reducing mouse allergen exposure may modulate the immunopathology underlying symptomatic pediatric allergic asthma, and that this occurs through epigenetic regulation. To test this hypothe...

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Pubblicato in:Environ Res
Autori principali: Miller, Rachel L., Zhang, Hanjie, Jezioro, Jacqueline, De Planell Saguer, Mariangels, Lovinsky-Desir, Stephanie, Liu, Xinhua, Perzanowski, Matthew, Divjan, Adnan, Phipatanakul, Wanda, Matsui, Elizabeth C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503684/
https://ncbi.nlm.nih.gov/pubmed/28454014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.envres.2017.04.025
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