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A topically-sprayable, activatable fluorescent and retaining probe, SPiDER-βGal for detecting cancer: Advantages of anchoring to cellular proteins after activation

SPiDER-βGal is a newly-developed probe that is activated by β-galactosidase and is then retained within cells by anchoring to intracellular proteins. Previous work has focused on gGlu-HMRG, a probe activated by γ-glutamyltranspeptidase, which demonstrated high sensitivity for the detection of perito...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Nakamura, Yuko, Mochida, Ai, Nagaya, Tadanobu, Okuyama, Shuhei, Ogata, Fusa, Choyke, Peter L., Kobayashi, Hisataka
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503628/
https://ncbi.nlm.nih.gov/pubmed/28467810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17080
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