Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma

Dishevelled-3 (Dvl3) is regarded as a binding hub with many different interacting partners. However, its regulation and mechanism on cancer stemness remain to be explored. In this study, we showed that Dvl3 was significantly overexpressed in human hepatocellular carcinomas (HCCs) and promoted cancer...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Tsui, Yu-Man, Sze, Karen Man-Fong, Tung, Edmund Kwok-Kwan, Ho, Daniel Wai-Hung, Lee, Terence Kin-Wah, Ng, Irene Oi-Lin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503623/
https://ncbi.nlm.nih.gov/pubmed/28455968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17049
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