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Selective induction of toxicity to human cells expressing human immunodeficiency virus type 1 Tat by a conditionally cytotoxic adenovirus vector.

The human immunodeficiency viruses (HIVs) primarily infect CD4+ T lymphocytes, leading eventually to the development of a systemic immune dysfunction termed acquired immunodeficiency syndrome (AIDS). An attractive strategy to combat HIV-mediated pathogenesis would be to eliminate the initial pool of...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Venkatesh, L K, Arens, M Q, Subramanian, T, Chinnadurai, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1990
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55036/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2247444/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.22.8746
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