Asiatic acid protects against cognitive deficits and reductions in cell proliferation and survival in the rat hippocampus caused by 5-fluorouracil chemotherapy

The chemotherapy drug, 5-fluorouracil (5-FU), has been reported to cause cognitive impairments in cancer patients. The drug also reduces cell proliferation and survival in the brain. Asiatic acid (AA) is a triterpene compound found in Centella asiatica that can protect against reduction of neurogene...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Chaisawang, Pornthip, Sirichoat, Apiwat, Chaijaroonkhanarak, Wunnee, Pannangrong, Wanassanun, Sripanidkulchai, Bungorn, Wigmore, Peter, Welbat, Jariya Umka
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503269/
https://ncbi.nlm.nih.gov/pubmed/28700628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180650
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