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Solution conformations of Zika NS2B-NS3pro and its inhibition by natural products from edible plants

The recent Zika viral (ZIKV) epidemic has been associated with severe neurological pathologies such as neonatal microcephaly and Guillain-Barre syndrome but unfortunately no vaccine or medication is effectively available yet. Zika NS2B-NS3pro is essential for the proteolysis of the viral polyprotein...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Roy, Amrita, Lim, Liangzhong, Srivastava, Shagun, Lu, Yimei, Song, Jianxing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503262/
https://ncbi.nlm.nih.gov/pubmed/28700665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180632
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