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A DNA gyrase-binding site at the center of the bacteriophage Mu genome is required for efficient replicative transposition.

We have discovered a centrally located site that is required for efficient replication of bacteriophage Mu DNA and identified it as a strong DNA gyrase-binding site. Incubation of Mu DNA with gyrase and enoxacin revealed a cleavage site 18.1 kilobases from the left end of the 37.2-kilobase genome. T...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Pato, M L, Howe, M M, Higgins, N P
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55030/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2174162/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.22.8716
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