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Treatment of NRAS-mutated advanced or metastatic melanoma: rationale, current trials and evidence to date

The disease course of BRAF (v-raf murine sarcoma viral oncogene homolog B1)-mutant melanoma has been drastically improved by the arrival of targeted therapies. NRAS (neuroblastoma RAS viral oncogene homolog)-mutated melanoma represents 15–25% of all metastatic melanoma patients. It currently does no...

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Detalhes bibliográficos
Publicado no:Ther Adv Med Oncol
Main Authors: Boespflug, Amélie, Caramel, Julie, Dalle, Stephane, Thomas, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502949/
https://ncbi.nlm.nih.gov/pubmed/28717400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834017708160
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