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Receptor for Advanced Glycation Endproduct Modulators: A New Therapeutic Target in Alzheimer’s Disease

INTRODUCTION: Reduction in the deposition of amyloid beta (Aβ) has been the primary target for Alzheimer’s disease (AD) therapeutics recently, but in clinical trials this approach has generally been unsuccessful. A common feature of AD pathology is a complex inflammatory component that could be a ta...

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Detalhes bibliográficos
Publicado no:Expert Opin Investig Drugs
Main Authors: Walker, Douglas, Lue, Lih Fen, Paul, Gaurav, Patel, Amar, Sabbagh, Marwan N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502774/
https://ncbi.nlm.nih.gov/pubmed/25586103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2015.1001490
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