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Kalirin Reduction Rescues Psychosis-Associated Behavioral Deficits in APPswe/PSEN1dE9 Transgenic Mice

Psychosis in Alzheimer disease (AD+P) represents a distinct clinical and neurobiological AD phenotype, and is associated with more rapid cognitive decline, higher rates of abnormal behaviors, and increased caregiver burden compared to AD without psychosis. On a molecular level, AD+P is associated wi...

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Bibliographic Details
Published in:Neurobiol Aging
Main Authors: Krivinko, JM, Erickson, SL, Abrahamson, EE, Wills, ZP, Ikonomovic, MD, Penzes, P, Sweet, RA
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502748/
https://ncbi.nlm.nih.gov/pubmed/28319837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.02.006
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