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Hypoxia-Responsive Polymersomes for Drug Delivery to Hypoxic Pancreatic Cancer Cells

Hypoxia in tumors contributes to overall tumor progression by assisting in epithelial-to-mesenchymal transition, angiogenesis, and metastasis of cancer. In this study, we have synthesized a hypoxia-responsive, diblock copolymer poly(lactic acid)–azobenzene–poly(ethylene glycol), which self-assembles...

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Detalhes bibliográficos
Publicado no:Biomacromolecules
Main Authors: Kulkarni, Prajakta, Haldar, Manas K., You, Seungyong, Choi, Yongki, Mallik, Sanku
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502721/
https://ncbi.nlm.nih.gov/pubmed/27303825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.6b00350
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