Mesenchymal Stem Cells Overexpressing Interleukin-10 Promote Neuroprotection in Experimental Acute Ischemic Stroke

Interleukin (IL)-10 is a contributing factor to neuroprotection of mesenchymal stem cell (MSC) transplantation after ischemic stroke. Our aim was to increase therapeutic effects by combining MSCs and ex vivo IL-10 gene transfer with an adeno-associated virus (AAV) vector using a rat transient middle...

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Bibliografske podrobnosti
izdano v:Mol Ther Methods Clin Dev
Main Authors: Nakajima, Masataka, Nito, Chikako, Sowa, Kota, Suda, Satoshi, Nishiyama, Yasuhiro, Nakamura-Takahashi, Aki, Nitahara-Kasahara, Yuko, Imagawa, Kiwamu, Hirato, Tohru, Ueda, Masayuki, Kimura, Kazumi, Okada, Takashi
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2017
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502709/
https://ncbi.nlm.nih.gov/pubmed/28725658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.06.005
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