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Predicting RNA hyper-editing with a novel tool when unambiguous alignment is impossible

BACKGROUND: Repetitive elements are now known to have relevant cellular functions, including self-complementary sequences that form double stranded (ds) RNA. There are numerous pathways that determine the fate of endogenous dsRNA, and misregulation of endogenous dsRNA is a driver of autoimmune disea...

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Pubblicato in:BMC Genomics
Autori principali: McKerrow, Wilson H., Savva, Yiannis A., Rezaei, Ali, Reenan, Robert A., Lawrence, Charles E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502491/
https://ncbi.nlm.nih.gov/pubmed/28693467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3898-9
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