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HOCl can appear in the mitochondria of macrophages during bacterial infection as revealed by a sensitive mitochondrial-targeting fluorescent probe

Macrophages, important cells of the innate immune system, can produce abundant HOCl in the cytoplasm to fight against bacteria. Recent studies suggest that mitochondria in macrophages play a role in antibacterial responses. During bacterial infection, however, it is uncertain whether HOCl is present...

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Publicado en:Chem Sci
Main Authors: Zhou, Jin, Li, Lihong, Shi, Wen, Gao, Xinghui, Li, Xiaohua, Ma, Huimin
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502397/
https://ncbi.nlm.nih.gov/pubmed/28717494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01562f
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